Table 3 Antimicrobial susceptibility determined by BIOLOG for Salmonella enterica mutants in comparison to the parental strain
From: Multiple adaptive routes of Salmonella enterica Typhimurium to biocide and antibiotic exposure
TRIR/BKCR/CHXR | BKCR | BKCR/CHXR/TRIHS | TRIHS | |||||
|---|---|---|---|---|---|---|---|---|
Chemicals | Inhibitor Family | NE/TRI1 | CHX/BKC3 | TRI/BKC3 | NE/BKC3 | TRI/AMP | BKC/CHX2 | CHX/AMP |
ANTIBIOTICS | ||||||||
Neomycin | aminoglycosides | R | R | R | R | R | R | S |
Paromomycin | S | S | S | S | ||||
Sisomicin | S | S | R | R | S | R | R | |
Chloramphenicol | amphenicols | S | S | S | ||||
Thiamphenicol | R | R | R | R | R | |||
Cefazolin | cephalosporins | R | ||||||
Ceftriaxone | S | |||||||
Amoxicillin | lactams | S | R | S | S | S | R | R |
Aztreonam | S | S | S | |||||
Carbenicillin | S | S | S | |||||
Carbenicillin (II) | R | |||||||
Phleomycin | DNA oxidants | R | ||||||
Cinoxacin | DNA topoisomerases inhibitors | S | S | S | S | S | R | |
Ciprofloxacin | R | R | R | R | ||||
Enoxacin | R | S | S | S | S | S | R | |
Nalidixic acid | R | S | S | R | S | S | R | |
Novobiocin | S | |||||||
Ofloxacin | S | S | S | S | S | |||
Pipemidic acid | R | |||||||
Hydroxyurea | folate antagonists | R | S | R | S | R | R | S |
Trimethoprim | R | R | R | R | R | |||
Troleandomycin | macrolides | R | R | R | ||||
Rifampicin | RNA polymerase inhibitors | S | ||||||
Penimepicycline | tetracyclines | S | S | S | R | S | ||
Tetracycline | S | |||||||
NON-ANTIBIOTICS | ||||||||
1-Hydroxypyridine-2-thione | chelators | S | S | S | ||||
5,7-Dichloro-8-OHquinoline | S | S | S | |||||
5-Chloro-7-iodo-8-OHquinoline | S | R | S | R | S | S | ||
8-Hydroxyquinoline | R | R | R | R | ||||
Fusaric acid | S | S | S | S | ||||
2-Phenylphenol | DNA intercalators | R | ||||||
Chloroxylenol | Fungicides | R | ||||||
Patulin | R | R | R | R | ||||
Colistin | Membrane active agents | S | S | S | S | S | S | R |
Polymyxin B | S | S | S | S | ||||
Polymyxin B (II) | R | |||||||
Poly-L-lysine | S | S | S | S | S | S | S | |
Alexidine | S | S | ||||||
Ornidazole | oxidizing agents | S | S | S | ||||
1-Chloro-2,4-dinitrobenzene | S | S | R | S | R | R | ||
Atropine | other drugs | S | S | |||||
Pridinol | R | R | R | R | R | |||
Propranolol | S | S | S | S | S | S | ||
Chlorpromazine | S | S | S | S | S | S | ||
Benzethonium chloride | QACs | S | S | S | R | S | S | R |
Cetylpyridinium chloride | S | |||||||
Sodium azide | respiration, uncoupler | S | ||||||
Thioridazine | S | S | S | |||||
Potassium chromate | toxic anions | S | S | S | S | S | R | |
Potassium tellurite (II) | S | R | R | R | S | S | ||
Sodium metaborate | S | S | S | S | S | S | S | |
Sodium tungstate | R | |||||||
Sodium periodate | R | R | ||||||
Antimony(III) chloride | toxic cations | R | R | R | R | R | ||
Cadmium chloride | R | R | ||||||
Thallium(I) acetate | R | R | ||||||
D,L-Methionine hydroxamate | other inhibitors | S | S | S | S | S | S | S |
Phenyl-methylsulfonyl-fluoride | S | S | S | S | S | S | ||
D-Serine | R | |||||||
6-Mercaptopurine | S | S | R | |||||
Compound 48/80 | S | S | ||||||