Table 1 Results from Fisher’s exact test. The odds ratio for Alzheimer’s Disease risk for individuals who were carriers of E318G and APOEε4 was higher than the odds ratio for those who only carried APOEε4, but the confidence intervals overlap
From: Presenilin E318G variant and Alzheimer’s disease risk: the Cache County study
Alzheimer’s risk based on E318G status and APOEε4 Status | ||||||
|---|---|---|---|---|---|---|
Strata | Cases | Controls | P value | OR (95 % CI) | Power | |
E318G + | APOEε4 (+) | 8 | 20 | 0.0172 | 3.8 (1.1–13.3) | 0.66 |
APOEε4 (−) | 8 | 77 | ||||
E318G – | APOEε4 (+) | 253 | 765 | <2.2 × 10−16 | 3.3 (2.7–4.0) | 1.0 |
APOEε4 (−) | 209 | 2080 | ||||