Table 2 Results from Fisher’s exact test. The odds ratios observed were higher for E318G+ individuals than E318G– individuals with the same number of APOEε4 alleles, but the 95 % confidence intervals for these groups overlap
From: Presenilin E318G variant and Alzheimer’s disease risk: the Cache County study
Alzheimer’s risk based on E318G status and number of APOEε4 Alleles | ||||||
|---|---|---|---|---|---|---|
Strata | Cases | Controls | P value | OR (95 % CI) | Power | |
E318G + | APOEε44 | 1 | 1 | 0.197 | 9.1 (0.1–759.3) | 0.04 |
APOEε4 (+) | 7 | 19 | 0.043 | 3.5 (1.0–12.7) | 0.16 | |
APOEε4 (−) | 8 | 77 | ||||
E318G – | APOEε44 | 36 | 48 | 2.4 × 10−15 | 7.5 (4.6–12.0) | 1.0 |
APOEε4 (+) | 217 | 717 | <2.2 × 10−16 | 3.0 (2.4–3.7) | 1.0 | |
APOEε4 (−) | 209 | 2080 | ||||