Fig. 2From: Structure-guided selection of specificity determining positions in the human KinomeExamples of the kind of clusterings selected by our algorithm. The axes correspond to the 2D, PCA-reduced feature vector representation of the pairwise distances between structures as described in the Methods section. Each point represents one structure. Red: known to bind, black: known to not bind, gray: binding affinity unknown. Discs: structures belonging to HPCs, circles: all other structuresBack to article page