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Table 1 Coverage of labeled structures, number of predicted affinities for unlabeled structures, as well as sensitivity, specificity, precision, and accuracy for HPC-based prediction of binding affinity

From: Structure-guided selection of specificity determining positions in the human Kinome

Strategy Cov. #pred. Sens. Spec. Prec. Acc.
1 83 % 215 0.486 1.000 0.921 0.904
2 83 % 520 1.000 0.887 0.783 0.929
3 15 % 1,084 0.617 1.000 0.921 0.932
4 71 % 364 1.000 0.900 0.806 0.937
  1. Each row summarizes the average over all 38 ligands for the corresponding strategy