Fig. 3
From: EpiTracer - an algorithm for identifying epicenters in condition-specific biological networks
Case study 1 (PARK2 overexpression in human glioma cell line). Data corresponding to overexpression of PARK2 in human glioma cell line (U251). a Human PPI network comprising of 10,306 nodes and 74,404 edges. Nodes colored red are upregulated upon perturbation, and nodes colored green are downregulated. (a1) Table of network properties. b Perturbation-specific *HAN (highest activity network), with network properties in table b1. c The 5 epicenters which were differentially expressed, along with their immediate neighbors d List of epicenters specific to the perturbation as well as global epicenters