Fig. 4
From: EpiTracer - an algorithm for identifying epicenters in condition-specific biological networks
PARK2 influence zone. Detailed biological interpretation of PARK2 influence zone. a The PARK2 influence zone consists of 118 nodes and 119 edges. Red colored nodes correspond to upregulated genes, and green corresponds to downregulated genes. The epicenter is depicted using a hexagon. b GO enrichement of genes in PARK2 influence zone shows that most genes are involved in cell-cycle regulation. c Nodes downstream of PARK2 d Mechanistic insights into cell-cycle dysregulation upon PARK2 overexpression