Fig. 1

Identification of novel L1 antisense promoter (ASP) transcripts using a computational pipeline. a Schematic representation of our method to identify L1 ASP transcripts. The coordinates of human spliced ESTs were intersected with L1s and gene exons to identify ESTs with a TSS antisense to an L1 and overlapping an exon of a cognate gene. L1 ASP transcripts that displayed an independent EST supporting L1 exonization were removed. b Total number of L1 ASP transcripts identified in the current report (n = 988) cross-referenced to known existing L1 ASP transcripts found in published reports including recently identified L1 ORF0 gene fusions and the C-GATE database. c Histogram of the total number of ESTs identified per gene for L1 ASP transcripts (n = 2015 ESTs, some overlapping multiple genes)