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Fig. 1 | BMC Genomics

Fig. 1

From: RNA-Seq analysis of Gtf2ird1 knockout epidermal tissue provides potential insights into molecular mechanisms underpinning Williams-Beuren syndrome

Fig. 1

Differential expression analysis. a, b Venn diagrams of the sets of differentially expressed genes (DEGs) generated using different methods for analyzing differential expression. a Genes up-regulated in KO, and (b) genes down-regulated in KO found using edgeR and DESeq2. c Multidimensional scaling (MDS) plot generated using edgeR showing clustering of samples with the 3 biological replicates of WT (black) and 3 biological replicates of KO (orange). d Heatmap generated using heatmap.2 function of the gplots package in R of the top 500 differentially expressed genes found using edgeR, with input being the logCPM values for these genes. Blue represents lower expression, red represents higher expression

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BMC Genomics

ISSN: 1471-2164

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