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Table 2 Classification, predicted ancestral serotypes and cps mutations of invasive nontypeable Streptococcus pneumoniae in South Africa, 2003–2013 (N = 39)

From: Genomic analysis of nontypeable pneumococci causing invasive pneumococcal disease in South Africa, 2003–2013

  1. Bold type represents serotypes included in PCV13
  2. SLV single-locus variant, differs at one of the seven alleles. DLV Double-locus variant, differs at two of the seven alleles
  3. None Novel ST and therefore no serotype/ST association exists
  4. ND not done, isolates have no cps genes
  5. N/A Not applicable, resembles nontypeable pneumococci from carriage (no cps genes, but instead have typical nontypeable genes)
  6. NP not predicted. Isolates have no cps genes and/or are associated with more than 1 serotype
  7. aAs per Streptococcus pneumoniae multilocus sequence typing database (http://pubmlst.org/spneumoniae/, accessed March 2015)
  8. bOther serotype/s associated with that ST. See comments
  9. c glf pseudo gene present within the cps locus