Fig. 2
From: Inferring metabolic pathway activity levels from RNA-Seq data
Expectation maximization approach to compute pathway activity. This bipartite graph consists of a set A representing reads/contigs/ORF/proteins and the set B is for ORFs/proteins/ortholog groups/EC (Enzyme Commission) numbers. The arcs represent mapping between elements of both sets. For our binary EM, the set A consists of contigs mapped to ortholog groups and the weight of each arc is 1