Table 2 IPA revealed the top canonical pathways altered by exposure to ZEA, E. coli, respectively ZEA+ E. coli
Nr. Ctr. | NAME | E. coli | ZEA | ZEA + E. coli | |||
|---|---|---|---|---|---|---|---|
p-value | Ratio | p-value | Ratio | p-value | Ratio | ||
1. | iNOS Signaling | 1.23E-06 | 9/44 (0.205) | - | - | - | - |
2. | MIF Regulation of Innate Immunity | 7.06E-06 | 8/41 (0.195) | - | - | - | - |
3. | IL-12 Signaling and Production in Macrophages | 8.15E-06 | 14/135 (0.104) | - | - | - | - |
4. | Glucocorticoid Receptor Signaling | 1.12E-05 | 20/261 (0.077) | - | - | - | - |
5. | JAK/Stat Signaling | 1.25E-05 | 10/72 (0.139) | - | - | - | - |
6. | Renin-Angiotensin Signaling | - | - | 3.47E-05 | 6/118 (0.051) | - | - |
7. | P2Y Purigenic Receptor Signaling Pathway | - | - | 5.73E-05 | 6.129 (0.047) | ||
8. | Ceramide Signaling | - | - | 7.6E-05 | 5/84 (0.06) | - | - |
9. | Melanocyte Development and Pigmentation Signaling | - | - | 8.51E-05 | 5.86 (0.058) | - | - |
10. | Unfolded protein response | - | - | 1.77E-04 | 4/54 (0.074) | - | - |
11. | IL-17A Signaling in Gastric Cells | - | - | - | - | 1.83E-06 | 6/25 (0.24) |
12. | IL-17A Signaling in Fibroblasts | - | - | - | - | 1.47E-05 | 6/35 (0.171) |
13. | Role of Tissue Factor in Cancer | - | - | - | - | 5.45E-05 | 9/110 (0.082) |
14. | PKCθ Signaling In T Lymphocytes | - | - | - | - | 9.41E-05 | 9/118 (0.076) |
15. | T Cell Receptor Signaling | - | - | - | - | 1.34E-04 | 8/97 (0.082) |