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Table 1 Statistics for the match and mismatch between major and canonical (or principal) isoforms

From: ISOexpresso: a web-based platform for isoform-level expression analysis in human cancer

 

No. of genes (n=26541)

 

Cancer types

No. of samples

mTPM >0

Percent increase b

  

mTPM=0

    
   

Matched a

Not matched

 
    

kCanon

nokCanon

 

KIRP_normal

32

7359

12721 (2438) c

3972 (1113)

2489 (1594)

 

KIRP_tumor

290

8089

11544 (2474)

4580 (1266)

2328 (1475)

15.3 %

COAD_normal

41

7751

12562 (2543)

3919 (1189)

2309 (1597)

 

COAD_tumor

460

8234

11805 (2442)

4291 (1298)

2211 (1443)

9.5 %

THCA_normal

59

7647

12389 (2363)

4019 (1071)

2486 (1489)

 

THCA_tumor

505

7964

11838 (2405)

4387 (1166)

2352 (1504)

9.2 %

PRAD_normal

52

7429

12546 (2493)

4104 (1077)

2462 (1565)

 

PRAD_tumor

497

7645

12042 (2549)

4445 (1228)

2409 (1523)

8.3 %

READ_normal

10

7402

12743 (2451)

3954 (1152)

2442 (1686)

 

READ_tumor

165

8140

11879 (2499)

4283 (1277)

2239 (1459)

8.3 %

UCEC_normal

35

7715

11641 (2284)

4763 (1191)

2422 (1518)

 

UCEC_tumor

545

7746

11226 (2515)

5152 (1323)

2417 (1551)

8.2 %

BLCA_normal

19

7986

11820 (2373)

4433 (1206)

2302 (1577)

 

BLCA_tumor

408

8057

11381 (2541)

4791 (1412)

2312 (1593)

8.1 %

KIRC_normal

72

7411

12712 (2423)

3941 (1098)

2477 (1604)

 

KIRC_tumor

533

7623

12166 (2387)

4240 (1174)

2512 (1627)

7.6 %

LUSC_normal

51

7251

12681 (2415)

4055 (1058)

2554 (1702)

 

LUSC_tumor

502

7350

12404 (2563)

4300 (1187)

2487 (1670)

6 %

STAD_normal

35

7866

12901 (2559)

3443 (1151)

2331 (1663)

 

STAD_tumor

415

7374

13017 (2520)

3608 (1196)

2542 (1723)

4.8 %

HNSC_normal

44

7831

12622 (3040)

3844 (1225)

2244 (1678)

 

HNSC_tumor

520

7881

12383 (2788)

3994 (1193)

2283 (1626)

3.9 %

LUAD_normal

59

7802

12228 (2185)

4146 (1069)

2365 (1533)

 

LUAD_tumor

516

7547

12263 (2401)

4274 (1163)

2457 (1622)

3.1 %

KICH_normal

25

7166

12787 (2420)

4020 (1098)

2568 (1599)

 

KICH_tumor

66

8362

11776 (2773)

4146 (1368)

2257 (1529)

3.1 %

LIHC_normal

50

9136

10714 (3129)

4786 (1963)

1905 (1504)

 

LIHC_tumor

370

8787

10782 (2860)

4907 (1769)

2065 (1534)

2.5 %

BRCA_normal

114

7396

12504 (2193)

4107 (1025)

2534 (1559)

 

BRCA_tumor

1097

7711

12224 (2378)

4190 (1162)

2416 (1575)

2 %

ESCA_normal

11

7544

12824 (2847)

3701 (1306)

2472 (1772)

 

ESCA_tumor

184

7136

13037 (2639)

3754 (1201)

2614 (1739)

1.4 %

  1. aThe number of genes whose major isoform is matched to at least one of UniProt-based and UCSC-based canonical and APPRIS principal isoforms
  2. bPercent increase in the number of genes corresponding to “kCanon” when condition is changed from normal to tumor
  3. cThe numbers in parentheses indicate the number of genes whose expression level (mTPM) is greater than or equal to 1
  4. mTPM = median transcripts per million
  5. kCanon = the genes whose canonical or principal isoform is known
  6. nokCanon = the genes whose canonical or principal isoform is not known