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Fig. 5 | BMC Genomics

Fig. 5

From: Extent of pre-translational regulation for the control of nucleocytoplasmic protein localization

Fig. 5

Number of motifs regulated by the different pre-translational regulation modes. Of the 175 NLSs considered, 68 are constitutive. The 107 alternatively regulated NLSs are classified with respect to 4 modes of regulation in panel a (left): direct alternative splicing of the encoding exon, differential translation initiation, differential translation termination and frameshift. Similarly, of the 120 NESs considered, 34 are constitutive and panel a (right) shows the regulation types of the 86 alternative NESs. Alternatively regulated NLSs and NESs are present in genes producing significantly more transcripts than constitutive NLSs and NESs as shown in b (NLS on the left panel and NES on the right)

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