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Table 1 Substitution rates in miRNA categories

From: Differences in molecular evolutionary rates among microRNAs in the human and chimpanzee genomes

  Substitution rates
1,214 miRNA   miRNAs Effective Length Subs. Human Subs. Chimp miRNAs Human (sd) miRNAs Chimp (sd) Flank. Human (sd) Flank. Chimpanzee (sd)
840 Primate specific miRNAs Cluster Clustered 67 5558 32 39 0.0058 (0.0014) 0.007 (0.0016) 0.0077 (0.0011) 0.0094 (0.0022)
Non-clustered 773 62048 341 394 0.0055 (0.0003) 0.0063 (0.0005) 0.0065 (0.0003) 0.007 (0.0006)
Copies Multiple 73 6323 30 31 0.0047 (0.0009) 0.0049 (0.0008) 0.0092 (0.0013) 0.0075 (0.0015)
Single 767 61283 343 402 0.0056 (0.0003) 0.0066 (0.0005) 0.0064 (0.0003) 0.0072 (0.0006)
Localization Intergenic 200 16539 97 109 0.0059 (0.0007) 0.0066 (0.0008) 0.0082 (0.0008) 0.0093 (0.0013)
Genic 516 40895 219 242 0.0054 (0.0004) 0.0059 (0.0004) 0.006 (0.0004) 0.006 (0.0006)
Exon 47 4031 23 19 0.0057 (0.0011) 0.0047 (0.0015) 0.0038 (0.0011) 0.0068 (0.0038)
intron 371 29243 160 180 0.0055 (0.0004) 0.0062 (0.0006) 0.0065 (0.0006) 0.0063 (0.0006)
374 conserved-beyond-primates mIRNAs Cluster Clustered 191 16615 26 40 0.0016 (0.0003) 0.0024 (0.0005) 0.0042 (0.0006) 0.0046 (0.0006)
Non-clustered 183 16264 21 35 0.0013 (0.0002) 0.0022 (0.0004) 0.0054 (0.0008) 0.0058 (0.0014)
Copies Multiple 226 199676 29 44 0.0015 (0.0003) 0.0022 (0.0004) 0.0049 (0.0007) 0.0056 (0.0014)
Single 148 13203 18 31 0.0014 (0.0003) 0.0023 (0.0005) 0.0048 (0.0006) 0.0045 (0.0007)
Localization Intergenic 142 12400 23 42 0.0019 (0.0004) 0.0034 (0.0007) 0.0052 (0.0008) 0.0053 (0.0008)
Genic 139 12415 15 21 0.0012 (0.0003) 0.0017 (0.0004) 0.0043 (0.0006) 0.0065 (0.0022)
Exon 7 639 0 0 0 (0) 0 (0) 0.0054 (0.0023) 0.0036 (0.0021)
Intron 110 9929 12 15 0.0012 (0.0003) 0.0015(0.0004) 0.0042 (0.0006) 0.0072 (0.0021)
Ancestral repeats 1479*100 119996 635.4 712.4 0.0053 (0.0002) 0.0059 (0.0003) 0 (0) 0 (0)
Cluster 14 40 3214 4 6 0.0012 (0.0006) 0.0019 (0.0014) 0.0032 (0.0013) 0.0054 (0.0015)
Cluster 19 28 2417 4 7 0.0017 (0.0007) 0.0029 (0.0011) 0.0103 (0.0021) 0.0085 (0.0026)
  1. Effective length; effectively analysed sequence in base pairs (i.e. Neither gaps nor INDELs); Chimp, chimpanzee; Subs., substitutions in the indicated lineage; sd, standard deviations of substitution rates from 100 bootstraps for miRNAs and flanking regions (Flank.)
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