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Table 1 The top significantly enriched GO BP, MF and MetaCore “Process Networks” annotationsa

From: Quantitative analyses of the hepatic proteome of methylmercury-exposed Atlantic cod (Gadus morhua) suggest oxidative stress-mediated effects on cellular energy metabolism

# A) GO processes In data FDR
1 Small molecule metabolic process 56 2.049E-11
2 Response to inorganic substance 29 4.840E-10
3 Macromolecular complex remodeling 10 4.840E-10
4 Plasma lipoprotein particle remodeling 10 4.840E-10
5 Protein-lipid complex remodeling 10 4.840E-10
6 Cholesterol efflux 10 1.124E-09
7 Glycerolipid catabolic process 11 1.124E-09
8 Single-organism metabolic process 76 1.931E-09
9 Metabolic process 121 1.931E-09
10 Plasma lipoprotein particle organization 10 2.287E-09
# B) GO Molecular functions In Data FDR
1 Oxidoreductase activity 19 7.654E-04
2 Catalytic activity 63 7.654E-04
3 Phosphatidylcholine-sterol
O-Acyltransferase activator activity
3 7.654E-04
4 Small molecule binding 37 7.654E-04
5 Cholesterol transporter activity 4 7.654E-04
6 Sterol transporter activity 4 7.654E-04
7 Antioxidant activity 6 7.654E-04
8 Poly(A) RNA binding 21 1.899E-03
9 Anion binding 36 2.555E-03
10 Nucleotide binding 32 2.621E-03
# C) Process Networks In Data FDR
1 Translation_Translation initiation 9 1.001E-02
2 Response to hypoxia and oxidative stress 8 1.999E-02
3 Cytoskeleton_Actin filaments 8 2.223E-02
4 Cell adhesion_Cell junctions 7 4.893E-02
  1. aOnly the top 10 enriched GO BP (A) and MF (B) are shown here, and the full list of top 50 significantly enriched (FDR < 0.05) GO BP and MF terms and the associated proteins are presented in Additional file 4: Table S3