Table 2 Identification of the major biological processes of the genes differentially expressed in hepatic tissuea
Biological process | Genes | ||
|---|---|---|---|
Level 1 | Level 2/3 | Symbol | Fold Change |
apoptotic process | negative regulation of apoptotic process | LOXL4 | 1.6 |
biological adhesion | cell adhesion | MYOM1 SPP1 MEP1B LOXL4 | −2.5 0.9 1.3 1.6 |
biological regulation | regulation of biological process | DLK1 SFRP1 ID1 LOXL4 | −2.5 −1.8 1.1 1.6 |
|  | regulation of molecular function | MYOM1 CDK5R1 PPP1R3B MEP1B LOC515676 | −2.5 0.8 1.1 1.3 1.9 |
cellular component organization or biogenesis | cellular component organization | SPP1 | 0.9 |
cellular process | cell communication | DLK1 MYOM1 SFRP1 MEP1B LOXL4 | −2.5 −2.5 −1.8 1.3 1.6 |
cell cycle | CDK5R1 SESN2 | 0.8 0.9 | |
developmental process | anatomical structure morphogenesis | SPP1 | 0.9 |
death | LOXL4 | 1.6 | |
ectoderm development | DLK1 MEP1B | −2.5 1.3 | |
mesoderm development | MYOM1 MEP1B | −2.5 1.3 | |
system development | DLK1 MYOM1 SFRP1 MEP1B IGLL1 | −2.5 −2.5 −1.8 1.3 2.1 | |
immune system process | antigen processing and presentation | LOC100126815 MGC126945 | −2.4 −1.8 |
immune response | LOC100126815 MGC126945 HP IGLL1 | −2.4 −1.8 −1.6 2.1 | |
macrophage activation | LOXL4 | 1.6 | |
localization | transport | DLK1 LOC509034 SAA3 CACNA2D1 MEP1B LOXL4 | −2.5 −1.5 −1.1 −1.0 1.3 1.6 |
metabolic process | catabolic process | HERC6 | 1.8 |
carbohydrate metabolic process | PPP1R3B | 1.1 | |
cellular amino acid metabolic process | PYCR1 | 1.5 | |
nucleobase-containing compound metabolic process | DLK1 ID1 | −2.5 1.1 | |
protein metabolic process | MYOM1 HP CDK5R1 MEP1B LOXL4 FUT5 HERC6 LOC515676 ISG15 | −2.5 −1.6 0.8 1.3 1.6 1.6 1.8 1.9 2.5 | |
multicellular organismal process | single-multicellular organism process | MYOM1 SFRP1 HP MEP1B LOXL4 | −2.5 −1.8 −1.6 1.3 1.6 |
reproduction | gamete generation | HP | −1.6 |
response to stimulus | cellular defense response | LOC100126815 MGC126945 LOXL4 | −2.4 −1.8 1.6 |
immune response | LOC100126815 MGC126945 HP IGLL1 | −2.4 −1.8 −1.6 2.1 | |
response to external stimulus | HP MEP1B | −1.6 1.3 | |
response to stress | HP | −1.6 | |
Not found |  | C20H5orf49 LOC789904 SLC22A9 CFH SLC26A10 SAA2 M-SAA3 LOC100847494 LOC100335975 LOC617654 | −1.9 −1.8 −1.7 −1.5 −1.4 −1.2 −1.1 −0.9 1.4 4.2 |
Unassigned | C4H7orf57 MT1E MT1A THRSP KIAA1324 NGEF GSTA5 ACMSD NHEDC1 NEFH G0S2 LOC524810 IFI27 IFI6 | −4.4 −3.4 −3.3 −1.7 −1.6 −1.4 −1.3 −1.2 −1.1 −1.1 1.9 2.6 3.3 3.7 | |