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Table 3 Panther gene list classification system for the genes differentially expressed in mammary gland tissuea

From: Supplements of vitamins B9 and B12 affect hepatic and mammary gland gene expression profiles in lactating dairy cows

Treatment Gene symbol Gene name Treatment regulation effect Molecular Function Biological Process Protein Class
B9
POSTN Periostin Up- receptor binding cell communication
cell-matrix adhesion
visual perception
sensory perception
mesoderm development
skeletal system development
muscle organ development
signaling molecule
cell adhesion molecule
FUT5 Alpha-(1,3)-Fucosyltransferase Up- transferase activity, transferring glycosyl groups protein glycosylation glycosyltransferase
ATP6V1G3 V-Type Proton Atpase Subunit G 3 Up- hydrolase activity
cation transmembrane transporter activity
proton-transporting ATP synthase activity, rotational mechanism
nucleobase-containing compound metabolic process
cation transport
ATP synthase
hydrolase
 LOC785756 androgen binding protein beta-like Down- Unassigned Unassigned Unassigned
MGC126945 uncharacterized protein MGC126945 Down- receptor activity B cell mediated immunity
antigen processing and presentation
cellular defense response
immunoglobulin receptor superfamily
major histocompatibility complex antigen
CIDEA cell death-inducing DFFA-like effector a Down- Unassigned induction of apoptosis Unassigned
B12
GPR110 G-Protein Coupled Receptor 110-Related Up- G-protein coupled receptor activity spermatogenesis
immune response
synaptic transmission
neurotransmitter secretion
mesoderm development
heart development
response to stress
intracellular protein transport
synaptic vesicle exocytosis
G-protein coupled receptor
antibacterial response protein
IRX6 iroquois homeobox 6 Up- sequence-specific DNA binding transcription factor activity
sequence-specific DNA binding transcription factor activity
transcription from RNA polymerase II promoter
ectoderm development
nervous system development
regulation of transcription from RNA polymerase II promoter
homeobox transcription factor
nucleic acid binding
RAB15 Ras-related protein Rab-15 Up- Unassigned Unassigned Unassigned
B9 + B12
 LOC509034 feline leukemia virus subgroup C receptor-related protein 2-like Down- transmembrane transporter activity transport Transporter
IDO1 indoleamine 2,3-dioxygenase 1 Down- Unassigned Unassigned Unassigned
SECTM1 SECTM1 protein Down- Unassigned Unassigned Unassigned
  1. Differentially expressed genes in mammary tissue were assigned to gene ontology pathways using the Panther tool. Some genes were not found in Panther genes list. Furthermore, among the genes ID found by the PANTHER system, some were not classified to a category. Only 3 genes ontology categories are presented: Molecular Function, Biological Process and Protein Class
  2. aClassification with the Panther gene list classification system of the genes differentially expressed in mammary tissue following supplementation with vitamin B9 (B9), vitamin B12 (B12) or both (B9 + B12) as compared to no vitamin treatment (Control)