Skip to main content

Table 3 Panther gene list classification system for the genes differentially expressed in mammary gland tissuea

From: Supplements of vitamins B9 and B12 affect hepatic and mammary gland gene expression profiles in lactating dairy cows

Treatment

Gene symbol

Gene name

Treatment regulation effect

Molecular Function

Biological Process

Protein Class

B9

  POSTN

Periostin

Up-

receptor binding

cell communication

cell-matrix adhesion

visual perception

sensory perception

mesoderm development

skeletal system development

muscle organ development

signaling molecule

cell adhesion molecule

  FUT5

Alpha-(1,3)-Fucosyltransferase

Up-

transferase activity, transferring glycosyl groups

protein glycosylation

glycosyltransferase

  ATP6V1G3

V-Type Proton Atpase Subunit G 3

Up-

hydrolase activity

cation transmembrane transporter activity

proton-transporting ATP synthase activity, rotational mechanism

nucleobase-containing compound metabolic process

cation transport

ATP synthase

hydrolase

 LOC785756

androgen binding protein beta-like

Down-

Unassigned

Unassigned

Unassigned

  MGC126945

uncharacterized protein MGC126945

Down-

receptor activity

B cell mediated immunity

antigen processing and presentation

cellular defense response

immunoglobulin receptor superfamily

major histocompatibility complex antigen

  CIDEA

cell death-inducing DFFA-like effector a

Down-

Unassigned

induction of apoptosis

Unassigned

B12

  GPR110

G-Protein Coupled Receptor 110-Related

Up-

G-protein coupled receptor activity

spermatogenesis

immune response

synaptic transmission

neurotransmitter secretion

mesoderm development

heart development

response to stress

intracellular protein transport

synaptic vesicle exocytosis

G-protein coupled receptor

antibacterial response protein

  IRX6

iroquois homeobox 6

Up-

sequence-specific DNA binding transcription factor activity

sequence-specific DNA binding transcription factor activity

transcription from RNA polymerase II promoter

ectoderm development

nervous system development

regulation of transcription from RNA polymerase II promoter

homeobox transcription factor

nucleic acid binding

  RAB15

Ras-related protein Rab-15

Up-

Unassigned

Unassigned

Unassigned

B9 + B12

 LOC509034

feline leukemia virus subgroup C receptor-related protein 2-like

Down-

transmembrane

transporter activity transport

Transporter

  IDO1

indoleamine 2,3-dioxygenase 1

Down-

Unassigned

Unassigned

Unassigned

  SECTM1

SECTM1 protein

Down-

Unassigned

Unassigned

Unassigned

  1. Differentially expressed genes in mammary tissue were assigned to gene ontology pathways using the Panther tool. Some genes were not found in Panther genes list. Furthermore, among the genes ID found by the PANTHER system, some were not classified to a category. Only 3 genes ontology categories are presented: Molecular Function, Biological Process and Protein Class
  2. aClassification with the Panther gene list classification system of the genes differentially expressed in mammary tissue following supplementation with vitamin B9 (B9), vitamin B12 (B12) or both (B9 + B12) as compared to no vitamin treatment (Control)