Fig. 4
From: Forward genetic screen of human transposase genomic rearrangements
PGBD5-associated HPRT1 structural variants contain terminal signal sequences. a Analysis of the sequences flanking structural variant breakpoints demonstrating association of specific signal sequence motifs in cells expressing GFP-PGBD5 (top), but not GFP control (bottom). X-axis denotes nucleotide sequence logo position, and y-axis denotes information content in bits. Black arrowheads mark the location of the breakpoints. b Breakpoint sequences of a representative structural variant (deletion bnd_11) showing PSS sequence at both breakpoints of a deletion