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Table 1 Large-scale distribution of the predicted 1,581,256 NIEBs along the 22 human autosomes

From: Evidence of selection for an accessible nucleosomal array in human

 

(% genome)

NIEB/kb

cov (%)

All NIEBs

100

0.59

9.0

L1 (GC <38 %)

33.3

0.54

9.5

L2 (38≤ GC <42 %)

32.3

0.63

9.6

H1 (42≤ GC <47 %)

21.4

0.65

9.0

H2 (47≤ GC <52 %)

9.2

0.56

6.9

H3 (52 % ≤ GC)

3.7

0.44

5.0

Early (MRT <0.36)

30.0

0.65

9.1

Medium (0.36≤ MRT <0.69)

40.0

0.59

8.9

Late (0.69≤MRT)

30.0

0.54

9.1

Low DNase (<14.3 reads/kb)

30.0

0.53

9.0

Medium DNase

40.0

0.60

9.3

High DNase (>29.3 reads/kb)

30.0

0.63

8.7

Low Recomb (<0.378 cM/Mb)

30.0

0.61

9.7

Medium Recomb

40.0

0.59

9.0

High Recomb (>1.681 cM/Mb)

30.0

0.58

8.4

Genes

47.1

0.61

9.2

Intergenes

51.6

0.57

8.9

  1. NIEB density was computed in 100 kb non-overlapping windows that were classified according to their GC content, MRT, DNase I sensitivity raw tag density and meiotic recombination rate (Methods). The last two rows correspond to mean NIEB densities computed in 23,329 genes (Methods) and complementary intergenic regions (Methods). The first column defines the region, the second column its corresponding genome coverage (%), the third column the mean NIEB density (NIEB/kb) and the fourth column, the corresponding coverage of this region by the set of NIEBs (%). For each row, we estimated the standard error of the mean NIEB density to be SEM <0.01
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BMC Genomics

ISSN: 1471-2164

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