From: Detection of high variability in gene expression from single-cell RNA-seq profiling
Simulation parameters | Regression results | |||||||
---|---|---|---|---|---|---|---|---|
# of cells | α | β | s | Prct (%) | \( \hat{\alpha} \) | \( \hat{\beta} \) | RMSE | RMSE (Eq. 9) |
1,000 | 0.15 | 1.2 | 1 | 10 | 0.1563 ± 0.0005 | 1.1965 ± 0.0018 | 0.0037 ± 0.0003 | 0.028 ± 0.002 |
30 | 0.1579 ± 0.0006 | 1.2017 ± 0.0019 | 0.0048 ± 0.0003 | 0.026 ± 0.001 | ||||
50 | 0.1612 ± 0.0009 | 1.2076 ± 0.0023 | 0.0071 ± 0.0005 | 0.027 ± 0.001 | ||||
2 | 10 | 0.1563 ± 0.0005 | 1.1961 ± 0.0019 | 0.0040 ± 0.0005 | 0.033 ± 0.007 | |||
30 | 0.1612 ± 0.0017 | 1.2015 ± 0.0024 | 0.0077 ± 0.0014 | 0.036 ± 0.001 | ||||
50 | 0.1713 ± 0.0014 | 1.2080 ± 0.0024 | 0.0147 ± 0.0012 | 0.050 ± 0.002 | ||||
3 | 10 | 0.1572 ± 0.0012 | 1.1963 ± 0.0026 | 0.0056 ± 0.0009 | 0.048 ± 0.008 | |||
30 | 0.1649 ± 0.0010 | 1.1997 ± 0.0027 | 0.0122 ± 0.0011 | 0.054 ± 0.002 | ||||
50 | 0.1775 ± 0.0012 | 1.2078 ± 0.0030 | 0.0225 ± 0.0011 | 0.096 ± 0.003 |