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Table 2 Gene Ontology and KEGG pathway annotation of DEGs between two groups

From: Whole blood transcriptional profiling comparison between different milk yield of Chinese Holstein cows using RNA-seq data

Category GO ID GO term P value No.of DEGs DEGs
BP GO:0006952 defense response 0.000001 15 KYNU, CARD9, OLR1, RSAD2, CCL5, TLR7, TNFRSF4, CXCL10, MIF, CCR3, HRH4, PLA2G7, THBS1, MX2, RAB27A
BP GO:0009611 response to wounding 0.000008 13 NRP1, OLR1, CCL5, TLR7, TPM1, TNFRSF4, CXCL10, MIF, CCR3, HRH4, PLA2G7, THBS1, RAB27A
BP GO:0006955 immune response 0.000024 14 KYNU, CARD9, OLR1, IFITM3, RSAD2, CCL5, TLR7, TNFRSF4, CXCL10, MIF, IGHE, TREM2, THBS1, RAB27A
BP GO:0006954 inflammatory response 0.000027 10 OLR1, CCR3, HRH4, PLA2G7, CCL5, THBS1, TNFRSF4, TLR7, MIF, CXCL10
BP GO:0006690 icosanoid metabolic process 0.001543 4 GGT5, CYP2J2, ALOX12, MIF
BP GO:0033559 unsaturated fatty acid metabolic process 0.001954 4 GGT5, CYP2J2, ALOX12, MIF
BP GO:0009615 response to virus 0.001958 5 CARD9, RSAD2, CCL5, MX2, TLR7
BP GO:0006631 fatty acid metabolic process 0.002770 6 LPL, GGT5, CYP2J2, CPT1A, ALOX12, MIF
BP GO:0032940 secretion by cell 0.003353 6 STX1A, LMF1, USE1, CCL5, RAB27A, CXCL10
BP GO:0051607 defense response to virus 0.004209 3 CARD9, RSAD2, TLR7
BP GO:0006633 fatty acid biosynthetic process 0.006735 4 LPL, GGT5, ALOX12, MIF
BP GO:0046394 carboxylic acid biosynthetic process 0.006891 5 LPL, GGT5, KYNU, ALOX12, MIF
BP GO:0016053 organic acid biosynthetic process 0.006891 5 LPL, GGT5, KYNU, ALOX12, MIF
BP GO:0046456 icosanoid biosynthetic process 0.009951 3 GGT5, ALOX12, MIF
BP GO:0006636 unsaturated fatty acid biosynthetic process 0.011894 3 GGT5, ALOX12, MIF
BP GO:0008015 blood circulation 0.012860 5 TCAP, OLR1, MYOF, TPM1, CXCL10
BP GO:0003013 circulatory system process 0.012860 5 TCAP, OLR1, MYOF, TPM1, CXCL10
BP GO:0051270 regulation of cell motion 0.014554 5 COL18A1, NRP1, THBS1, TPM1, CXCL10
BP GO:0046903 secretion 0.015412 6 STX1A, LMF1, USE1, CCL5, RAB27A, CXCL10
BP GO:0016192 vesicle-mediated transport 0.021730 8 STX1A, RABEP2, HIP1R, USE1, TRAPPC5, CCL5, THBS1, RAB27A
BP GO:0002252 immune effector process 0.027651 4 CARD9, RSAD2, TLR7, RAB27A
BP GO:0002684 positive regulation of immune system process 0.028807 5 CARD9, IL13RA1, THBS1, TNFRSF4, TLR7
BP GO:0002544 chronic inflammatory response 0.028923 2 CCL5, THBS1
BP GO:0045087 innate immune response 0.029812 4 KYNU, TLR7, RAB27A, MIF
BP GO:0051240 positive regulation of multicellular organismal process 0.031168 5 CARD9, CCL5, THBS1, TPM1, TLR7
BP GO:0045785 positive regulation of cell adhesion 0.034610 3 THBS1, TPM1, ALOX12
BP GO:0006968 cellular defense response 0.035673 3 CCR3, CCL5, TNFRSF4
BP GO:0033273 response to vitamin 0.041171 3 ALPL, KYNU, PMF1
BP GO:0002694 regulation of leukocyte activation 0.047354 4 IL13RA1, THBS1, TNFRSF4, MIF
BP GO:0031349 positive regulation of defense response 0.049365 3 CARD9, CCL5, TLR7
BP GO:0030334 regulation of cell migration 0.049479 4 COL18A1, THBS1, TPM1, CXCL10
BP GO:0000267 cell fraction 0.002965 13 STX1A, KYNU, CYB5R2, CYP2J2, OLR1, HIP1R, SLC6A4, CCL5, CPT1A, PYGM, HRH4, ABCC4, CA4
CC GO:0005886 plasma membrane 0.009603 27 ALPL, STEAP4, NRP1, IFITM3, SLC6A4, SLC16A12, RSAD2, TNFRSF4, TPM1, HRH4, TGM3, THBS1, IL13RA1, MYOF, RAB27A, LPL, STX1A, OLR1, ZP3, FADD, GGT5, TARP, CCR3, CA4, ABCC4, TREM2, ALOX12
CC GO:0044433 cytoplasmic vesicle part 0.010180 5 STX1A, HIP1R, ABCC4, THBS1, RAB27A
CC GO:0030659 cytoplasmic vesicle membrane 0.025142 4 STX1A, HIP1R, ABCC4, RAB27A
CC GO:0044421 extracellular region part 0.027958 10 COL18A1, LPL, OGN, ZP3, PLA2G7, PMF1, CCL5, THBS1, MIF, CXCL10
CC GO:0005624 membrane fraction 0.028767 9 STX1A, CYP2J2, OLR1, HIP1R, HRH4, SLC6A4, ABCC4, CA4, CPT1A
CC GO:0012506 vesicle membrane 0.031088 4 STX1A, HIP1R, ABCC4, RAB27A
CC GO:0005615 extracellular space 0.034524 8 COL18A1, LPL, PLA2G7, PMF1, CCL5, THBS1, MIF, CXCL10
CC GO:0005626 insoluble fraction 0.034688 9 STX1A, CYP2J2, OLR1, HIP1R, HRH4, SLC6A4, ABCC4, CA4, CPT1A
CC GO:0030141 secretory granule 0.048228 4 STX1A, ABCC4, THBS1, RAB27A
MF GO:0019955 cytokine binding 0.013930 4 CCR3, IL13RA1, THBS1, TNFRSF4
MF GO:0008144 drug binding 0.028489 3 PYGM, SLC6A4, TLR7
KEGG PATHWAY hsa04620 Toll-like receptor signaling pathway 0.029157 4 FADD, CCL5, TLR7, CXCL10