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Fig. 6 | BMC Genomics

Fig. 6

From: An integrative genomics approach for identifying novel functional consequences of PBRM1 truncated mutations in clear cell renal cell carcinoma (ccRCC)

Fig. 6

Hypothesized mechanisms of PBRM1 truncated mutation functions in the tumor genetics of ccRCC. Hyper-methylation and altered miRNAs expression were found associated with PBRM1 truncated mutation in ccRCC. Up-regulated genes and pathways were shown in red (left) while down-regulated genes and pathways were shown in blue (right)

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