Fig. 6From: An integrative genomics approach for identifying novel functional consequences of PBRM1 truncated mutations in clear cell renal cell carcinoma (ccRCC)Hypothesized mechanisms of PBRM1 truncated mutation functions in the tumor genetics of ccRCC. Hyper-methylation and altered miRNAs expression were found associated with PBRM1 truncated mutation in ccRCC. Up-regulated genes and pathways were shown in red (left) while down-regulated genes and pathways were shown in blue (right)Back to article page