Towards precision medicine-based therapies for glioblastoma: interrogating human disease genomics and mouse phenotypes

Table 1 The top-ranked categories of GBM-specific mouse phenotypes detected through disease genetics

Rank	Phenotype category	Example phenotype
1	Tumorigenesis	Increased glioblastoma incidence
2	Nervous system phenotype	Abnormal astrocyte morphology
3	Hematopoietic system	Abnormal hematopoiesis
	Phenotype
4	Mortality/aging	Decreased survivor rate
5	Immune system phenotype	Decreased leukocyte cell number

ISSN: 1471-2164