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Table 2 Molecular classification of breast carcinoma

From: Comprehensive comparison of molecular portraits between cell lines and tumors in breast cancer

Classification Immunoprofile Other characteristics
Luminal A ER+/PR+/HER2-; ER+/PR-/HER2-; ER-/PR+/HER2-, Low tumor grade, Low expression of proliferation marker Ki67
Luminal B ER+/PR+/HER2+; ER+/PR-/HER2+; ER-/PR+/HER2+ High tumor grade, High expression of proliferation marker Ki67
HER2-enrichment ER-/PR-/HER2+; ER-/PR-/HER2+; ER-/PR-/HER2+ High tumor grade, High expression of proliferation marker Ki67
Basal-Like ER-/PR-/HER2- High tumor grade, High expression of proliferation marker Ki67