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Table 2 Molecular classification of breast carcinoma

From: Comprehensive comparison of molecular portraits between cell lines and tumors in breast cancer

Classification

Immunoprofile

Other characteristics

Luminal A

ER+/PR+/HER2-; ER+/PR-/HER2-; ER-/PR+/HER2-,

Low tumor grade, Low expression of proliferation marker Ki67

Luminal B

ER+/PR+/HER2+; ER+/PR-/HER2+; ER-/PR+/HER2+

High tumor grade, High expression of proliferation marker Ki67

HER2-enrichment

ER-/PR-/HER2+; ER-/PR-/HER2+; ER-/PR-/HER2+

High tumor grade, High expression of proliferation marker Ki67

Basal-Like

ER-/PR-/HER2-

High tumor grade, High expression of proliferation marker Ki67