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Table 1 Enrichment analysis of the 15 gene modules that are specific to tumor samples in lung cancer

From: A matrix rank based concordance index for evaluating and detecting conditional specific co-expressed gene modules

Module Size GO BP term (p-value) Cytoband (p-value) TF (p-value)
4 162 Epidermis development (p = 8.762E-23); 1q21-q22 (p = 3.354E-06); AP1 (p = 2.177E-04, 22 genes);
2p24.3 (p = 5.021E-06) AREB6 (p = 9.900E-04, 8 genes)
5 159 neuron differentiation (p = 1.516E-07); 6q14.2 (p = 1.796E-04); PAX4 (p = 1.046E-05, 9 genes);
generation of neurons (p = 2.105E-07) 5q33 (p = 2.686E-04) MSX1 (p = 2.088E-04, 7 genes)
9 98 Neurogenesis (p = 1.490E-06);   MSX1 (p = 2.875E-06, 7 genes);
central nervous system development (p = 2.543E-06)   RNGTGGGC UNKNOWN (p = 3.383E-05, 11 genes)
17 62 meiotic nuclear division (p = 1.035E-04); 7p15.3-p15.1 (p = 1.676E-03);  
meiotic cell cycle (p = 1.349E-04) 12q22-q24.1 (p = 1.676E-03)
19 55 cellular glucuronidation (p = 2.634E-05); 4q13 (p = 2.202E-04);  
uronic acid metabolic process (p = 3.005E-05) 4q31.3-q32 (p = 1.474E-03)
25 48 glutamate decarboxylation to succinate (p = 4.577E-06); 4q21.22 (p = 1.646E-06);  
glutamate catabolic process (p = 9.526E-05) 8p11.22 (p = 1.485E-04)
38 36 calcium ion export (p = 2.626E-05) 7q21.3 (p = 8.602E-06);  
9p21.3 (p = 2.647E-04)
44 33 vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure (p = 2.381E-06); 7p12.2 (p = 1.729E-05); RORA1 (p = 6.429E-03, 3 genes);
baroreceptor response to increased systemic arterial blood pressure (p = 1.424E-05) 11p15.2-p15.1 (p = 9.241E-04) ERR1 (p = 7.357E-03, 3 genes)
50 30 fatty acid derivative metabolic process (p = 1.751E-07); 4q28-q32 (p = 1.673E-03) WGTTNNNNNAAA UNKNOWN  (p = 2.278E-03, 4 genes);
icosanoid metabolic process (p = 1.751E-07) FOXO4 (p = 1.168E-02, 6 genes)
66 21   4p16.3 (p = 2.197E-9, 5 genes); 13 genes on 4p13-16 E2F1 (p = 9.854E-4, 3 genes)
67 21   9q21.33 (p = 5.973E-05); RACTNNRTTTNC UNKNOWN  (p = 3.031E-05, 3 genes)
9q22.32 (p = 1.652E-04); 18 genes on 9q21-34
70 20   1q22-q23.2 (p = 5.196E-04)  
8q22-q23 (p = 1.038E-03)
81 18   21q22.3 (p = 2.655E-05)  
84 18   4q31.23 (p = 6.329E-06); 4q31 (p = 1.242E-05); 12 genes on 4q23-31 CREB (p = 1.568E-04, 3 genes)
116 13   Xp11.23 (p = 6.422E-04) MEIS1 (p = 1.089E-03, 3 genes)