Table 1 Enrichment analysis of the 15 gene modules that are specific to tumor samples in lung cancer

4

162

Epidermis development (p = 8.762E-23);

1q21-q22 (p = 3.354E-06);

AP1 (p = 2.177E-04, 22 genes);

2p24.3 (p = 5.021E-06)

AREB6 (p = 9.900E-04, 8 genes)

5

159

neuron differentiation (p = 1.516E-07);

6q14.2 (p = 1.796E-04);

PAX4 (p = 1.046E-05, 9 genes);

generation of neurons (p = 2.105E-07)

5q33 (p = 2.686E-04)

MSX1 (p = 2.088E-04, 7 genes)

9

98

Neurogenesis (p = 1.490E-06);

MSX1 (p = 2.875E-06, 7 genes);

central nervous system development (p = 2.543E-06)

RNGTGGGC UNKNOWN (p = 3.383E-05, 11 genes)

17

62

meiotic nuclear division (p = 1.035E-04);

7p15.3-p15.1 (p = 1.676E-03);

meiotic cell cycle (p = 1.349E-04)

12q22-q24.1 (p = 1.676E-03)

19

55

cellular glucuronidation (p = 2.634E-05);

4q13 (p = 2.202E-04);

uronic acid metabolic process (p = 3.005E-05)

4q31.3-q32 (p = 1.474E-03)

25

48

glutamate decarboxylation to succinate (p = 4.577E-06);

4q21.22 (p = 1.646E-06);

glutamate catabolic process (p = 9.526E-05)

8p11.22 (p = 1.485E-04)

38

36

calcium ion export (p = 2.626E-05)

7q21.3 (p = 8.602E-06);

9p21.3 (p = 2.647E-04)

44

33

vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure (p = 2.381E-06);

7p12.2 (p = 1.729E-05);

RORA1 (p = 6.429E-03, 3 genes);

baroreceptor response to increased systemic arterial blood pressure (p = 1.424E-05)

11p15.2-p15.1 (p = 9.241E-04)

ERR1 (p = 7.357E-03, 3 genes)

50

30

fatty acid derivative metabolic process (p = 1.751E-07);

4q28-q32 (p = 1.673E-03)

WGTTNNNNNAAA UNKNOWN  (p = 2.278E-03, 4 genes);

icosanoid metabolic process (p = 1.751E-07)

FOXO4 (p = 1.168E-02, 6 genes)

66

21

4p16.3 (p = 2.197E-9, 5 genes); 13 genes on 4p13-16

E2F1 (p = 9.854E-4, 3 genes)

67

21

9q21.33 (p = 5.973E-05);

RACTNNRTTTNC UNKNOWN  (p = 3.031E-05, 3 genes)

9q22.32 (p = 1.652E-04); 18 genes on 9q21-34

70

20

1q22-q23.2 (p = 5.196E-04)

8q22-q23 (p = 1.038E-03)

81

18

21q22.3 (p = 2.655E-05)

84

18

4q31.23 (p = 6.329E-06); 4q31 (p = 1.242E-05); 12 genes on 4q23-31

CREB (p = 1.568E-04, 3 genes)

116

13

Xp11.23 (p = 6.422E-04)

MEIS1 (p = 1.089E-03, 3 genes)