Fig. 3

The plot summarizes simultaneously the miRNAs families detected on this survey and the source data that supports their prediction. The miRNA families and data source are represented by segments on the circle. miRNA families are arranged to the right side of the circle and species from which queries belong to or the HMM method used to search for homologous in D. vexillum are arranged around the left side. The source data is shown as merged lines originating from each species or the HMM method to its supported candidate in D. vexillum. Candidate location names are presented on the blue inside of the circle. Every small square under each gray band represents species or the HMM method that supports the candidate detection; they are coloured according to different taxa or method: yellow for vertebrate species, blue for basal chordates species, green for invertebrates or the single-celled organism and red for the de novo HMM method. Tags are Anolis carolinensis (ACA), Branchiostoma floridae (BFL), Caenorhabditis elegans (CEL), Ciona intestinalis (CIN), Ciona savignyi (CSA), Danio rerio (DRE), Latimeria chalumnae (LCH), Oikopleura dioica (ODI), Petromyzon marinus (PMA), Saccharomyces cerevisiae (SCE), Xenopus tropicalis (XTR), and (NO) to the HMMs strategy. As one example, the mir-8 family was detected for queries of 3 vertebrate species (DRE, ACA and LCH) and basal chordates (CIN and CSA); locus located on the contig dvex119671 supported by (DRE and ACA) and of two basal chordates (CIN, CSA), dvex434162 by two vertebrates (DRE and LCH) and one basal chordate (CIN), dvex462351 by (DRE) and dvex665523 by (ACA). Notice that mir-281 was only predicted by the HMM strategy and none candidates were supported by queries from S. cerevisiae or the tunicate species O. dioica. mir-(3,210,233,374,449,651,672) were supported only by basal chordate data source