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Fig. 3 | BMC Genomics

Fig. 3

From: Pangenome and immuno-proteomics analysis of Acinetobacter baumannii strains revealed the core peptide vaccine targets

Fig. 3

Pan- and core genome plot of A. baumannii strains. The X-axis in the graphs denotes all the A. baumannii strains included in our study and Y-axis indicates the number of genes expressed in each strain. The green line in the chart indicates the gradual pan-genome expansion and the red line shows the core genome development/conservation with addition of each genome. The blue bars represent the number of genes present in each of the strains. Comparative genomics analysis of all the included strains led us to pan-genome estimation, comprising of 7606 coding sequences, of which 2445 represented core genome. In the pan-core plot, there is a subsequent increase in pan-genome with the addition of next genome, and the core genome decreases with the addition of second genome and so on, till a conserved set of 2445 genes attained representing the core gene repertoire. The stable core genome suggests that it can be explored for identification of conserved vaccine candidates. The gradual extension of the pan-genome with addition of new genome suggests an open pan-genome of A. baumannii. The number of genes that each strain contains can be documented from comprehensive statistical analysis given earlier in Table 1

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