The Rat microRNA body atlas; Evaluation of the microRNA content of rat organs through deep sequencing and characterization of pancreas enriched miRNAs as biomarkers of pancreatic toxicity in the rat and dog

Table 2 Pancreas enriched miRNAs conserved between rat and dog

Rat pancreas	Sequence (5′-3′)	Dog Pancreas	Sequence (5′-3′)
miR-101c	TACAGTACTGTGATAACTGATC	miR-101c	ACAGTACTGTGATAACTGACC
miR-141-3p	TAACACTGTCTGGTAAAGATG	miR-141	TAACACTGTCTGGTAAAGATG
miR-193b-3p	AACTGGCCCACAAAGTCCCGCT	miR-193a-3p	AACTGGCCTACAAAGTCCCAGTT
miR-200c-3p	TAATACTGCCGGGTAATGATGGA	miR-200c	TAATACTGCCGGGTAATGATGGA
miR-216a-5p	TAATCTCAGCTGGCAACTGTG	miR-216a	TAATCTCAGCTGGCAACTGTGA
miR-216b-5p	AAATCTCTGCAGGCAAATGTGA	miR-216b	AAATCTCTGCAGGCAAATGTGA
miR-320-3p	AAAAGCTGGGTTGAGAGGGCGA	miR-320b;miR-320c	AAAAGCTGGGTTGAGAGGGAA
miR-4286	ACCCCACTCCTGGTACCA	miR-4286	ACCCCACTCCTGGTACCA
miR-5100	ATCCCAGCGGTGCCTCCA	miR-5100	GTTCGAATCCCAGCGGTG
miR-217-5p	TACTGCATCAGGAACTGACTGGA	miR-217	ATACTGCATCAGGAACTGATT
miR-375	TTTGTTCGTTCGGCTCGCGTGA	miR-375	TTTGTTCGTTCGGCTCGCGTGA

Tissue enriched miRNAs conserved between rat and dog were identified and are shown above. These miRNAs were analyzed for changes in the serum in rat and dog caerulein toxicology studies. Bases underlined indicate bases that are not conserved between the rat and dog isomiRs with the highest sequencing counts

ISSN: 1471-2164