Table 5 Top 20 functions of predicted gene targets of differentially expressed miRNAs in sera and exosomes
Highly expressed miRNAs in sera | Highly expressed miRNAs in exosomes | ||
|---|---|---|---|
Category | B-H p-value | Category | B-H p-value |
Cellular Assembly and Organization | 6.09E-06-9.75E-02 | Cell Death and Survival | 6.84E-14-3.44E-02 |
Cellular Function and Maintenance | 6.09E-06-9.75E-02 | Cellular Assembly and Organization | 8.85E-14-2.77E-02 |
Molecular Transport | 1.09E-05-9.68E-02 | Cellular Function and Maintenance | 8.85E-14-3.45E-02 |
Cancer | 6.32E-05-9.68E-02 | Cellular Growth and Proliferation | 4.07E-13-3.45E-02 |
Cell Death and Survival | 9.31E-05-9.68E-02 | Cell Morphology | 1.09E-10-3.34E-02 |
Organismal Survival | 9.31E-05-6.44E-02 | Cellular Movement | 8.05E-09-2.79E-02 |
Cellular Growth and Proliferation | 9.31E-05-9.75E-02 | Cancer | 2.61E-08-3.24E-02 |
Cell Morphology | 2.20E-04-9.75E-02 | Molecular Transport | 4.45E-07-3.21E-02 |
Cardiovascular System Development and Function | 2.94E-04-9.68E-02 | Cardiovascular System Development and Function | 8.40E-07-3.43E-02 |
Organismal Development | 2.94E-04-9.68E-02 | Organismal Development | 8.40E-07-3.45E-02 |
Infectious Disease | 7.70E-04-9.68E-02 | Organismal Survival | 1.38E-06-2.44E-02 |
Gene Expression | 7.70E-04-9.68E-02 | Tissue Development | 1.79E-05-3.34E-02 |
Cellular Movement | 8.00E-04-9.68E-02 | Gene Expression | 2.31E-05-2.13E-02 |
Cell-mediated Immune Response | 1.23E-03-9.68E-02 | Cellular Development | 2.89E-05-3.45E-02 |
Cellular Development | 1.23E-03-9.75E-02 | Nervous System Development and Function | 5.47E-05-3.23E-02 |
Hematological System Development and Function | 1.23E-03-9.75E-02 | Skeletal and Muscular System Development and Function | 6.43E-05-3.23E-02 |
Hematopoiesis | 1.23E-03-9.75E-02 | Neurological Disease | 6.97E-05-3.18E-02 |
Lymphoid Tissue Structure and Development | 1.23E-03-9.75E-02 | Lipid Metabolism | 1.19E-04-3.18E-02 |
Tissue Development | 1.82E-03-9.75E-02 | Small Molecule Biochemistry | 1.19E-04-3.21E-02 |
Connective Tissue Development and Function | 2.01E-03-9.75E-02 | Psychological Disorders | 1.55E-04-2.44E-02 |