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Table 2 Top disease and function altered as response to ZEA exposure

From: Microarray based gene expression analysis of Sus Scrofa duodenum exposed to zearalenone: significance to human health

ID Top diseases and functions Score Focus molecules
1 Cell Morphology, Cellular Assembly and Organization, Cellular Function and Maintenance 40 34
2 Metabolic Disease, Neurological Disease, Organismal Injury and Abnormalities 38 33
3 Auditory Disease, Hereditary Disorder, Neurological Disease 38 33
4 Molecular Transport, Hereditary Disorder, Connective Tissue Disorders 35 32
5 Digestive System Development and Function, Endocrine System Development and Function, Organ Morphology 31 30
6 Cellular Movement, Cell-To-Cell Signalling and Interaction, Nervous System Development and Function 31 30
7 Cancer, Cell Death and Survival, Organismal Injury and Abnormalities 31 30
8 Gene Expression, Protein Synthesis, RNA Post-Transcriptional Modification 29 29
9 Cell Death and Survival, Cell Morphology, Infectious Disease 29 29
10 Cardiovascular System Development and Function, Cancer, Cardiovascular Disease 29 29
11 Connective Tissue Disorders, Immunological Disease, Inflammatory Disease 28 28
12 Tissue Development, Post-Translational Modification, Cell Cycle 28 28
13 Cell Cycle, DNA Replication, Recombination, and Repair, Cellular Compromise 26 27
14 Nucleic Acid Metabolism, Small Molecule Biochemistry, Cell Cycle 26 27
15 DNA Replication, Recombination, and Repair, Cell Cycle, Reproductive System Development and Function 26 27
16 Cellular Growth and Proliferation, Embryonic Development, Organ Development 26 27
17 RNA Post-Transcriptional Modification, Developmental Disorder, Hereditary Disorder 26 27
18 Developmental Disorder, Hereditary Disorder, Skeletal and Muscular Disorders 26 27
19 Protein Synthesis, Cancer, Organismal Injury and Abnormalities 26 27
20 Energy Production, Lipid Metabolism, Small Molecule Biochemistry 26 27
21 Cellular Assembly and Organization, Inflammatory Disease, Inflammatory Response 24 26
22 Lipid Metabolism, Molecular Transport, Small Molecule Biochemistry 24 26
23 RNA Post-Transcriptional Modification, Carbohydrate Metabolism, Cellular Compromise 24 26
24 Amino Acid Metabolism, Small Molecule Biochemistry, Cell Signaling 24 26
25 Infectious Disease, Organismal Injury and Abnormalities, Dermatological Diseases and Conditions 24 26
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BMC Genomics

ISSN: 1471-2164

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