Fig. 2

Impact of individual variables on survival prediction of the multivariable model (ridge) for OS if predictors are changed by +1 SD. Survival probabilities are estimated at 36 months of follow-up time. The length of the lines is proportional to the change in prediction in case the value of the indicated variable changes by +1 SD (left: negative effect; right: positive effect). Variables are ranked according to the absolute changes in prediction which also corresponds to the order within the combined model (Table 3). Gene profiling variables not used for follow-up analyses are displayed in grey color