Fig. 3

The CodY binding to newly identified CodY-mediated genes in B. anthracis. The CodY binding enrichment to its binding motif proximal to the CodY-mediated genes identified in the transcriptome is quantitatively measured by chromatin immunoprecipitation and qRT-PCR. The enrichment of the CodY binding motif is relative to the abundance of the target sequences in the input sample. The values are presented as the means ± SE. *; the level of statistical significance between CodY and IgG enrichment was determined by one-way ANOVA followed by Tukey’s HSD post hoc test (*: p < 0.05, **: p < 0.01)