Fig. 4

Expressional patterns of pathway-specific genes in response to environmental deprivation. Expressional fold-change values of differentially expressed CodY-mediated genes that were assessed in either a iron-depleted condition (R^-Fe), b glucose starved condition (R^-Glu), or c aerated condition (R^-Bic) are presented in the heat maps and bar graphs. Changes in the mRNA expression are presented in color with green indicating a decrease or red indicating an increase in the read count relative to the parental 34 F2 strain. The term p is the statistical significance by the Kruskal-Wallis H nonparametric test for the expression trend of each gene in the wild-type (34 F2) and codY null (BCD22) strains under different conditions. Statistical significance in bar graphs were determined by ANOVA followed by Tukey’s HSD post hoc test (*: p < 0.05, **: p < 0.01)