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Fig. 2 | BMC Genomics

Fig. 2

From: Rapid evolutionary adaptation to growth on an ‘unfamiliar’ carbon source

Fig. 2

Gene group expression comparison. a Ratio between (log) expression on xylulose and glucose of all genes comprising the amino-acid biosynthesis expression module (n = 136), for wild type and evolved strains. Expression was averaged over all twelve strains and normalized per gene (materials and methods). b Wild type vs. evolved mean (log) expression (xylulose/glucose) of various gene groups, averaged over the twelve strains. Error bars represent standard error. Gene group names: mitochondrial ribosomal proteins (mito. RP), amino-acid biosynthesis (aa), GCN4-regulated (GCN4), genes down-regulated as part of the environmental stress response (ESR down), protein synthesis (protein), ribosomal proteins (RP), ribosome biogenesis and assembly (ribi) and genes up-regulated as part of the environmental stress response (ESR up). c Same as in B but for gene groups regulated by various transcription factors (n = 66, gray dots), RP regulators FHL1 and SFP1 (red dots) and the amino-acid biosynthesis regulator GCN4 (green dot)

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