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Fig. 8 | BMC Genomics

Fig. 8

From: Molecular and structural considerations of TF-DNA binding for the generation of biologically meaningful and accurate phylogenetic footprinting analysis: the LysR-type transcriptional regulator family as a study model

Fig. 8

Architecture of the TFBSs of the LysR-type TF family in Gammaproteobacteria revealed by PProCoM analysis. A common characteristic of the members of the LysR-type family in Gammaproteobacteria is that their coding genes and corresponding target genes are transcribed in divergent orientations, and their intergenic regions present two or three inverted repeated motifs, IR1, IR2 and IR3. The architecture of the intergenic regions of the six TFs analyzed in our study is summarized. Clear conservations of motif length and inter-motif distance suggest that there are similarities in their molecular regulatory mechanisms

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