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Fig. 6 | BMC Genomics

Fig. 6

From: Viral deep sequencing needs an adaptive approach: IRMA, the iterative refinement meta-assembler

Fig. 6

Assembled consensus differences to baseline. Known baseline consensus sequences correspond to an A/equine/Detroit/3/64-like sample. Differences versus the baselines are shown for (a) H7 HA and (b) N7 NA starting references and for the progression of assembled consensus sequences corresponding to each maximum IRMA round. A non-iterative assembly (Bowtie2, local, very sensitive) using each starting reference is shown for comparison. Match, mismatch, deletion, and insertion states are relative to the baseline in blue, red, yellow, and green respectively while white is used for a baseline gap in the alignment created by non-baseline insertions. Percent identity versus the baseline sequence is shown to the right of each graphed sequence. The phylogenetic trees depict approximate placement of the starting references on our H7 and N7 datasets, with the baseline labeled as “+”

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