Fig. 4

Loci with distinct subpopulation copy number profiles. a Manhattan plot of V_ST values (Y-axis) for each 100 bp bin (X-axis) in the Cryptococcus gattii genome. The horizontal red line represents the upper 99 % percentile cutoff. Points above this line are considered significantly differentiated CNVs. The five highest V_ST loci that contain genes are highlighted in yellow (supercontig 11 contains two of the five loci). b Gene copy number estimates for the five highest V_ST gene-containing loci. The gene ID and V_ST ID are reported for each locus. Blue, orange, and gray points represent VGIIa, VGIIb, and VGIIc isolates. Functional annotation (PFam domains or gene name) is provided below each plot