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Table 2 Counter-expressed (CE) and co-expressed (CoE) genes

From: RNAseq analysis of heart tissue from mice treated with atenolol and isoproterenol reveals a reciprocal transcriptional response

Gene response

FDR < 5×10−2

FDR < 10−2

FDR < 10−3

FDR < 10−4

up-regulated by ISO but down-regulated by ATE (CEISO ATE)

34

22

14

10

down-regulated by ISO but up-regulated by ATE (CEISO ATE)

34

24

15

10

total for counter-expressed (CE)

68

46

29

20

up-regulated by ISO and ATE (CoEISO ATE)

2

0

0

0

down-regulated by ISO and ATE (CoEISO ATE)

0

0

0

0

total for co-expressed (CoE)

2

0

0

0

  1. The number of counter-expressed (CE) and co-expressed (CoE) genes obtained for samples pooled by treatment is presented at four different FDR thresholds. CE genes survive stringent FDR thresholds while the significance of the few co-expressed genes is much less robust