Fig. 5

Human coexpression network mapping the evolutionary age on highly correlated nodes. Representation of the coexpression complex network –like a galaxy– that includes 1691 protein nodes related with 19,615 interactions. This network corresponds to a subset of the larger coexpression network produced, which included 2298 proteins and 20,005 interactions (provided in Additional file 2). The subset is done to include only the groups that had at least five linked proteins. The color mapping of the nodes correspond to the eight stages that were identified in the evolutionary study (as reflected in the labels included at the top right). The network also includes numbers for 11 major subnetworks –clusters of closely related proteins that include more than 20 nodes– considered as major constellations in the galaxy of nodes. Three panels on the right show an enlarged view of three subnetworks corresponding to: ribosomal proteins (5), mitochondrial proteins (10) and angiogenesis proteins (11)