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Fig. 2 | BMC Genomics

Fig. 2

From: CNARA: reliability assessment for genomic copy number profiles

Fig. 2

CBS versus step-fitting for 200 set of simulated copy number profiles. Scatter plot of the number of segments detected by CBS (purple) and step-fitting (green), plotted against the number of true CNA segments. In group A, the number of segments recovered by CBS approximates true CNA segments very well; the number of segments recovered by CBS is close to that of step-fitting. In group B, both methods fitted noise in which CBS found more change-points than step-fitting in general. In group C, CBS recovered much more segments than the number of true segments, whereas step-fitting found majority of CNA segments well

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