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Fig. 2 | BMC Genomics

Fig. 2

From: Genome-wide identification and characterisation of HOT regions in the human genome

Fig. 2

Association of HOT regions with functional elements. ab Examples of HOT regions (red line) overlapping microRNA a and repetitive elements b. Peaks are observed in cell types consistent with known functions of the microRNAs and repetitive elements (pink line). c Examples of known cell-selective experimentally validated distal, non-promoter cis-regulatory elements. Shown above each set of DNaseI data are schematics displaying HOT regions relative to the genes they control. d Examples of colocalisation of DMV (blue) and UMR (pink) with HOT regions (red) in a cell-type-specific manner. See also Additional file 1: Figure S4 and Additional file 2: Tables S6–S7

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