Skip to main content
Fig. 1 | BMC Genomics

Fig. 1

From: Impaired telomere maintenance in Alazami syndrome patients with LARP7 deficiency

Fig. 1

In vitro behavior of LARP7 knockdown cells. Extent of LARP7 knockdown normalized to Actin protein expression in Hela3 cells (a) demonstrates ~90 % loss of LARP7 protein in all three shRNAs examined (b) (n = 1 for each knockdown). Loss of LARP7 is accompanied by reduction in telomerase enzymatic activity (c) (n = 3) and progressive time-dependent telomere shortening (d)

Back to article page