Fig. 1
Phylogenetic structure (Neighbor-joining trees) according to a a genome-wide sequence alignment, and b presence or absence of genes in 128 genomes from nine species of the genus Bordetella. The bordetellae evolved into 3 clades of species: the phylogenetically oldest clade C formed by B. petrii and B. ansorpii, clade B formed by B. trematum, B. hinzii, B. avium and B. holmesii, and clade A containing the classical bordetellae B. bronchiseptica, B. parapertussis and B. pertussis. The Neighbor-joining trees were rooted based on tree topologies of 16SÂ rRNA gene and 23SÂ rRNA gene sequence and ATP-synthase protein phylogenies (Additional file 1: Figure S1)