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Fig. 3 | BMC Genomics

Fig. 3

From: Single-cell RNA sequencing reveals dynamic changes in A-to-I RNA editome during early human embryogenesis

Fig. 3

Recoding RNA-editing events in cells during early embryonic stages. a Heatmap of non-synonymous RNA-editing events in cells during early embryonic stages. Each row represents a cell, and each column represents a non-synonymous A-to-I editing site. Frequently edited genes are highlighted with dashed lines. Blank regions, uniquely mapped reads < 4, not qualified for RNA-editing determination. b Changes in non-synonymous editing frequency are negatively associated with the gene expression of AZIN1. Left, changes in AZIN1’s editing frequency; middle, changes in AZIN1’s expression; right, editing frequency is negatively associated with the AZIN1 expression level, each open circle represents one single cell. * P < 0.05; ** P < 0.01; *** P < 0.001

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