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Table 2 Genes differentially expressed (DE) (B value at least 2.945, p-value below 0.01, fold change at least 2, and expression levels in all replicates at any population at least 100) during maturation of adult erythroblasts in SEM-F were selected as shown, and submitted to gene ontology analysis using GeneCoDis

From: Distinct gene expression program dynamics during erythropoiesis from human induced pluripotent stem cells compared with adult and cord blood progenitors

Comparison GO category Corrected Hyp. p Value
Upregulated d0 to d4 Mitotic cell cycle 2e−91
Downregulated d0 to d4 Cytokine-mediated signalling 7e−20
Antigen processing and presentation 7e−18
Upregulated d12 to d14 Nucleus/cell cycle arrest 7e−6
Downregulated d12 to d14 Purine metabolism 4e−11
Ribosome biosynthesis 8e−9
Mitotic cell cycle 7e−8
  1. Significantly-scoring ontologies are shown, together with p-values presented as the more stringent corrected hypergeometric (Hyp) p-values produced by GeneCoDis