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Fig. 4 | BMC Genomics

Fig. 4

From: Cross-phenotype association tests uncover genes mediating nutrient response in Drosophila

Fig. 4

The diacylglycerol kinase rdgA governs body mass, starvation resistance, and lifespan. a and b Trait association to rdgA genotype in the DGRP. Data are as in Fig. 1a-b, except that an intronic variant in rdgA is analyzed. c-e Validation of rdgA function in laboratory strains. c Each trace reports survival of a strain harboring a transposon insertion in rdgA (mutant) or isogenic wild-type control, pre-treated for 10 days on the indicated diet and then switched to acute starvation media. d Each column reports body mass per fly of the indicated strain, with genotypes as in c (n = 2 populations of 15 flies per condition). e Each column reports whole body triglyceride levels normalized to body mass in the indicated strain, with genotypes as in c (n = 1 population of 15 flies per condition). Symbols and abbreviations are as in Fig. 1. For strain details see Additional file 1: Table S6

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