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Table 1 Phenotypes and chemical exposure classes used in the analysis of module cluster activation

From: Mining kidney toxicogenomic data by using gene co-expression modules

Name

Class

P1a

Kidney-cortex, tubule, necrosis

P2a

Kidney-tubule, regeneration

C1

Hepatotoxicants

C2

Fluoroquinolone antibiotics

C3

Epithelial growth factor receptor kinase inhibitors

C4

Estrogen receptor modulators

C5

Statins

C6

Fibrates

  1. aP1 and P2 were defined based on histopathology data