Single nucleotide variant discovery of highly inbred Leghorn and Fayoumi chicken breeds using pooled whole genome resequencing data reveals insights into phenotype differences

Table 7 Gene ontology terms from DAVID for variant regions with greatest difference (F _ST = 1)

GO Terms	Count	P-value
Nucleoside binding	630	6.90E-13
Purine nucleoside binding	626	4.30E-13
Adenyl nucleotide binding	622	3.50E-13
Nucleotide binding	869	9.10E-13
Purine nucleotide binding	745	2.90E-12
Adenyl ribonucleotide binding	585	1.20E-11
ATP binding	581	1.70E-11
Ribonucleotide binding	708	5.20E-11
Purine ribonucleotide binding	708	5.20E-11
Protein kinase activity	263	1.60E-07
Protein amino acid phosphorylation	273	7.30E-05
Atp-binding	243	1.50E-05
Nucleoside-triphosphatase regulator activity	129	1.80E-05
Gtpase regulator activity	125	3.10E-05
Protein serine/threonine kinase activity	168	3.70E-05
Extracellular ligand-gated ion channel activity	49	4.00E-05
Nucleotide-binding	300	1.00E-04
Phosphorus metabolic process	361	9.20E-04
Phosphate metabolic process	361	9.20E-04
Enzyme activator activity	78	2.90E-04
Nucleotide phosphate-binding region: ATP	103	2.50E-02
Gtpase activator activity	63	1.10E-03
Identical protein binding	112	1.50E-03
Ligand-gated ion channel activity	64	1.50E-03
Ligand-gated channel activity	64	1.50E-03

Functional categories from DAVID representing the genes that had F _ST value’s of 1. GO Terms from DAVID based on F _ST values of 1 for comparison of variant position between populations. Benjamini Corrected p-value cut-off α = 0.05

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