Table 1 The computation time for S2SEM and SML methods of one replicate for the simulations of common variants
From: A new statistical framework for genetic pleiotropic analysis of high dimensional phenotype data
Time(s)/replicate | Phenotypes 10, Common SNPs 10 | Phenotypes 30, Common SNPs 30 | Phenotypes 100, Common SNPs 100 | |||
|---|---|---|---|---|---|---|
Sample | S2SEM | SML | S2SEM | SML | S2SEM | SML |
100 | 0.712 | 0.825 | 5.148 | 16.386 | 273.873 | 353.402 |
300 | 0.926 | 1.598 | 7.058 | 37.006 | 123.936 | 873.426 |
500 | 1.228 | 2.560 | 9.037 | 58.360 | 143.593 | 1535.544 |
800 | 1.850 | 4.230 | 11.967 | 94.564 | 170.799 | 2470.602 |
1100 | 2.463 | 6.315 | 15.541 | 130.116 | 309.795 | 4098.201 |
1400 | 2.972 | 8.755 | 18.856 | 169.985 | 218.933 | 5269.562 |
1700 | 3.736 | 12.032 | 23.879 | 212.400 | 285.213 | 4989.240 |
2000 | 4.515 | 15.473 | 27.664 | 252.855 | 311.480 | 5973.181 |
2300 | 5.517 | 19.388 | 33.685 | 297.721 | 375.167 | 7268.095 |
2600 | 6.488 | 23.515 | 38.413 | 347.531 | 625.959 | 8950.179 |
2900 | 7.646 | 28.127 | 45.708 | 393.149 | 724.829 | 10455.262 |